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Biochemistry Introduction to Biochemistry

DNA

Overview

  • All cellular organisms uses DNA (deoxyribonucleic acid) to store genetic information
  • In all biological macromolecules there’s an intimate relationship between structure and function
    • E.g. DNA’s structure makes it great at storing information

DNA’s construction

  • DNA is a linear polymer, which means they are large molecules made up of many smaller molecules
Definition of a polymer

A polymer is a molecule made up of numerous small molecules called monomers that are joined together to form a larger molecule. The word “polymer” is made up of two parts: “poly” which means “many,” and “mer” which means “unit.” A linear polymer means just a long straight chain.

Polymer structures
Polymer structures
  • The small molecules that make up DNA are called nucleotides.
  • Each nucleotide contains a phosphate group, a sugar molecule (called deoxyribose), and a nitrogenous base.
The structure of a nucleotide
  • Join to each deoxyribose is one of four possible bases: adenine (A), cytosine (C), guanine (G), and thymine (T).